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Pure Innovation Biotech Limited

Company

Pure Innovation Biotech was founded with a vision to provide niche markets with specialized recombinant biopharmaceuticals. We have extensive experience in R&D, process development, fermentation and purification. We have invented a cost-effective industrial-scale GMP DNA production platform and a protein purification platform, which are suitable for production of DNA vaccines and recombinant proteins respectively for veterinary use. We have considerable network of veterinary research and commercial partners in China & Asia. We have many know-hows in plasmid DNA and recombinant proteins production processes and portfolio of technologies are available for collaboration and transfer.

Pure Innovation Biotech is specialized in contract research and services for development of new biotech products, especially veterinary DNA vaccines and protein subunit vaccines. Our robust industrial-scale cost-effective plasmid DNA production platform can produce kilograms level of injectable plasmid DNA without using expensive column chromatography. This non-chromatographic DNA manufacturing platform is suitable for producing different sizes and different construct design of plasmid DNA. Excellent quality with high percentage of supercoiled plasmid DNA and low endotoxin level meets stringent human injectable standards. In our protein purification platform, excretory recombinant protein expression system in E.coli can produce up to 1g/L of protein. This technique utilizing signal peptide simplifies the purification procedure since the proteins can be secreted into the fermentation broth. No breakage of bacteria cells and only conventional column chromatography is needed to produce tens of grams of highly purified protein (>95%).